Structural Heart Solutions
Aran Biomedical’s range of capabilities offer diverse approaches to cover structural heart implants, enabling novel solutions for next generation devices. A combination of custom fabrics, PTFE, electrospun materials and elastomeric coatings can be employed to develop frame coverings that meet the increasing challenges required from new devices.
Textile Frame Covering
Custom designed implantable medical fabrics, whether woven, knitted or braided, can be developed for use in structural heart implants, such as implantable valves and annuloplasty rings. The choice of material, fabric thickness, pore size, strength and compliance, are just some of the characteristics that can be optimised to your requirements. The fabric can also be laser trimmed to avoid fraying and shape formed to conform to the underlying implant.
Sutureless Fabric Assembly
Aran Biomedical has developed proprietary techniques for applying sutureless fabric covers onto structural heart frames. Removing the need for sutures to attach fabric onto a frame, can help to reduce profile, while dramatically improving labour time and resource requirements.
Annuloplasty rings are an established surgical device used for the repair of mitral valves. Aran Biomedical offers braided and tubular knit fabrics that can be used in an annuloplasty ring outer sheath. The fabric can be shape formed, laser machined, sewn, bonded or ultrasonically welded, depending on the design configuration and assembly requirements.
Whether flexible, semi-rigid or stiff in design, a core can be developed for the annuloplasty ring to meet preferred mechanical performance. Custom tethers or sutures can also be developed to facilitate device placement.
PTFE Covered Structural Heart Frame
PTFE is widely used for a diverse range of structural heart implants, such as occlusion devices, heart failure implants and heart valve frames.
Aran Biomedical offers PTFE covering for the most challenging implant geometries, including conical, flared and bulbous designs. In many cases, integration of PTFE onto the frame, avoids the requirement for labour intensive and highly technical suturing. Given an established clinical history of use in vascular indications it is often preferred as an alternative to textile covering options.
Electrospun Covered Structural Heart Frame
Aran Biomedical can also create electrospun scaffolds as a discrete membrane or apply electrospun fibres directly onto stents and similar metal frame implants. The microporous structure of electrospun material is well known to encourage tissue ingrowth.
The composition of the electrospun fabric or covering can be tailored as required, such as modifying porosity, thickness, fibre alignment and fibre diameter. There is an extremely diverse range of resorbable and non-resorbable materials that are suitable for electrospun processing, each with unique mechanical and physical properties.
Coated Textile Covering
In certain structural heart indications it may be necessary to coat textiles, for example, to create an atraumatic surface where the textile may be in contact with native valve leaflets, to reduce permeability, to facilitate removal of the implant over time or to promote certain blood surface properties. Aran Biomedical can apply a range or resorbable and non-resorbable coatings to textiles to enable this functionality. Uniform, high quality polymeric coatings can be applied to a very high tolerance and low profile, with the grade chosen to accommodate preferred mechanical properties.